Research Interest
Developing parametric and nonparametric statistical methods to detect genomic imprinting and maternal effects under different study designs.
Testing for association in a heterogeneous sample and its application on tumor clustering based on gene signatures
Analyzing chromatin interaction by paired-end tag sequencing data
Constructing 3D structure of Chromosomes based on Hi-C data
Asymptotic properties of spacings around an order statistics
Publications
H. MANSOURI & F. ZHANG, Simultaneous rank tests in analysis of covariance based on pairwise ranking. Submitted.
F. ZHANG & S. LIN. (2020) Imprinting and maternal effect detection using partial likelihood incorporating nearby loci. Eur J Hum Gene. doi: 10.1038/s41431-020-0590-3. [Epub ahead of print]
D. Wang*, T. WANG, A. Gill, T. HILLIARD, F. CHEN, A.L. KARAMYSHEV, & F. Zhang*. (2020) Uncovering the cellular capacity for intensive and specific feedback self-control of the argonautes and MicroRNA targeting activity. Nucleic Acids Research. gkaa20. (* co-corresponding authors)
D.P. Chen, F. ZHANG & S. LIN. AIJ: Joint Test for Simultaneous Detection of Imprinting and Allelic Expression Imbalance. Mathematical Biosciences and Engineering, 2020, 17(1): 366-386.
F. ZHANG, A. KHALILI, S. LIN. (2019) Imprinting and maternal effect detection using partial likelihood based on discordant sibship data. Statistica Sinica. 29: 1915-1937.
W. JIANG, Z. GUO, N. LAGES, W. ZHENG, D. FELIERS, F. ZHANG & D. WANG. (2018) Multi-parameter analysis of cellular coordination of multiple transcriptome regulation mechanisms. Scientific Reports. 8(1): 5742.
M. TODA, F. ZHANG & B. ATHUKORALLAGE. (2018) Mathematical models of beta barrels. PROTEINS: Structure, Function, and Bioinformatics. 86(1): 35-42.
F. ZHANG & D. WANG. (2017) The pattern of microRNA binding site distribution. Genes. 8(11): 296.
F. ZHANG , J. DING & S. LIN. (2017) Testing for associations of opposite directionality in a heterogeneous population. Statistics in BioSciences. 9(1): 137-159.
Z. Qin, B. Li, K. N. Conneely, H. Wu, M. Hu, D. Ayyala, Y. Park, V. Jin, F. ZHANG, H. Zhang, L. Li & S. Lin. (2016) Statistical Challenges in Analyzing Methylation and Long-Range Chromosomal Interaction Data. Statistics in Biosciences. 1-22.
F. ZHANG*, A. KHALILI* & S. LIN. (2015) Optimum Study Design for Detecting Imprinting and Maternal Effects Based on Partial Likelihood. Biometrics. 72(1): 95-105. (* co-first authors)
H. N. NAGARAJA, K. BHARATH & F. ZHANG. (2015) Spacings Around an Order Statistic. Annals of the Institute of Statistical Mathematics. 67: 515-540.
F. ZHANG & S. LIN. (2014) Nonparametric method for detecting imprinting effect using all members of general pedigrees with missing data. Journal of Human Genetics. 59: 541-548.
F. ZHANG & S. LIN. (2014) Detection of Imprinting Effects for Hypertension Based on General Pedigrees Utilizing All Affected and Unaffected Individuals. BMC proceedings. 8(Suppl 1):S52.
